Publications

Trazodone succinate — new opportunities for pharmacological correction of situational behavioral abnormalities in dogs and cats

Currently, the interest of veterinarians and owners in the pharmacological correction of situational behavioral disorders in companion animals has increased significantly. To quickly correct deviant behavior in dogs and cats, veterinarians use some of the psychotropic drugs used in human medicine, in particular, trazodone, an antidepressant antagonist / serotonin reuptake inhibitor.

Toxicological evaluation of Supramil® tablets, an anhelmintic drug for dogs and cats

The article presents the results of studies of the toxicological characteristics of the drug for veterinary use Supramil® tablets based on R-praziquantel and milbemycin oxime. The results of toxicometry and observational data on experimental animals make it possible to attribute the finished dosage form of the medicinal product Supramil® tablets to hazard class IV “Substances of low hazard” in accordance with GOST 12.1.007 – 76.

Rapid assessment of the clinical status and metabolic profile of female cats with different methods of sexual function regulation

According to the analytical agency Dalia Research in February 2017, about 33% and 23% of worldwide population, respectively, keep dogs and cats at home; when it comes to Russia, the cat is the most popular pet. Cats are present in more than half of households, and about 20% of owners keep several cats [1]. The problem of undesirable behavior of female cats during estrus is familiar to every owner; it causes serious inconvenience and reduces the pleasure of communicating with the animal [2-4].

Efficacy of the new anthelmintic drug Supramil® tablets in intestinal helminthiases of dogs and cats

The effectiveness of a new anthelmintic drug for dogs and cats Supramil® tablets was studied. Therapeutic efficacy of the drug Supramil® tablets after a single application in dogs and puppies with spontaneous invasions of intestinal nematodes and/or cestodes at a dose of 2.5 mg/kg for R-praziquantel and 0.5 mg/kg for milbemycin oxime in toxocariasis, toxascariasis, ankylostomosis, trichuriasis , dipylidiosis, teniasis, mesocestoidosis, as well as with mixed nematode-cestodesis invasions was 100%.

About interferons

INTERFERONS (IFN) is a common name that currently combines a number of proteins with similar structural and functional properties, which in the vast majority of cases are actively produced by the body cells when they are infected with a virus. These proteins are the most important components of the body's innate non-specific defense against infections and tumor transformations. Interferons were discovered by Isaacs and Lindemann in 1957 as antiviral agents, however, during their subsequent investigation it was detected that the functions of interferons in the cell are not limited to antiviral action: the properties common to this vast group of proteins also include antiproliferative activity (the ability to suppress cell reproduction), which later determines the possibility to inhibit the development of malignant neoplasms, and the ability to influence the state of the immune system, i.e., to perform the role of immunomodulators in the body.

Safe and effective use of the oral bihormonal drug for the long-term regulation of reproductive function in home cats

The article presents the results of monitoring the safety of prolonged use of the oral bihormonal contraceptive drug SEX BARRIER® for delaying and interrupting estrus in home cats by their owners. The use of the bihormonal contraceptive preparation SEX BARRIER® in the home cats by the owners does not lead to disturbances in the genital area, clinical status, morphological and biochemical parameters of animals blood. All owners have confirmed the 100 % effectiveness of the bi-hormonal preparation SEX BARRIER® for both interruption and delay of estrus.

Comparative characteristics of Monohormonal and Bihormonal progestogen containing drugs for suppression of the behavioral manifestations of the estrus in female cats

This article presents the comparative characteristics of bihormonal and monohormonal progestogen containing contraceptive drugs and the analysis of the safety of their use on small domestic animals. Evaluation of the risks of complications in the application of hormonal drugs to suppress the behavioral manifestations of estrus in female cats is given. It is concluded that the bihormonal preparations are more effective and safer than monohormonal drugs.

Ovarian remnant syndrome in female cats as a long-term adverse effect of surgical sterilization

It has been determined that in a part (13%) of female cats with ovariohysterectomy manifestations of estrus eventually resume. When determining the levels of sex hormones in the blood of this animal group, a high content of progesterone was detected, by 7-fold exceeding the level of the hormone in the blood of spayed cats without the estrus manifestations, and almost corresponding to its content in control animals.

The study assessing efficacy and safety of the bi-hormonal contraceptive drug during the long-term experiment

Correction of sexual function in domestic animals, in particular, in female cats and dogs, remains an important veterinary problem as of today. One of the main practical tasks during the studies on regulation of sexual function in animals kept at home is to suppress the manifestations of estrus, which cause a lot of trouble to the cats’ owners. There are two alternative approaches to solving this problem: surgical (spaying) and conservative method, involving the use of HCD.

Вы здесь